General Information

  • ID:  hor002912
  • Uniprot ID:  P38497
  • Protein name:  Lom-AG-myotropin-2
  • Gene name:  NA
  • Organism:  Locusta migratoria (Migratory locust)
  • Family:  Myotropic peptide family
  • Source:  animal
  • Expression:  Male accessory glands.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Locusta (genus), Oedipodinae (subfamily), Acrididae (family), Acridoidea (superfamily), Acridomorpha, Acrididea (infraorder), Caelifera (suborder), Orthoptera (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  AHRFAAEDFGALDTA
  • Length:  15
  • Propeptide:  AHRFAAEDFGALDTA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic peptide.
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-P62329-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    AF-P62329-F1.pdbhor002912_AF2.pdbhor002912_ESM.pdb

Physical Information

Mass: 184162 Formula: C70H102N20O23
Absent amino acids: CIKMNPQSVWY Common amino acids: A
pI: 4.37 Basic residues: 2
Polar residues: 2 Hydrophobic residues: 8
Hydrophobicity: -6 Boman Index: -2553
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 59.33
Instability Index: -419.33 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  NA
  • Title:  Isolation, identification and synthesis of Lom-AG-myotropin II, a novel peptide in the male accessory reproductive glands of Locusta migratoria.